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Screening and determination of methamphetamine and amphetamine in the blood, urine and stomach contents in emergency medical care and autopsy cases

Authors
Journal
Journal of Clinical Forensic Medicine
1353-1131
Publisher
Elsevier
Publication Date
Volume
2
Issue
1
Identifiers
DOI: 10.1016/1353-1131(95)90036-5
Disciplines
  • Medicine

Abstract

Abstract Methamphetamine (MA) and amphetamine (AMP) were screened and their levels were determined using the Toxi-Lab ® thin-layer chromatography system and gas chromatography-mass spectrometry, respectively, in the blood, urine and stomach contents from 211 emergency medical care and 417 autopsy cases. MA and AMP were detected in 5 emergency medical cases, and the blood MA and AMP concentrations ranged from 0.697-0.041 μmol/100 g and from 0.0944-0.0003 μmol/100 g, respectively. MA and AMP were detected in 19 autopsy cases, in which blood MA and AMP concentration ranged from 14.3-0.123 μmol/100 g and from 0.256-0.0017 μmol/100 g, respectively. The autopsy cases included 5 cases of sudden death with blood MA concentration of less than 3 μmol/100 g. MA and AMP screening and determination in emergency medical care and autopsy cases provide useful information and are indispenable in clarifying the dimensions of MA abuse in Japan.

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