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The Ethics of Switch/Simplify in Antiretroviral Trials: Non-Inferior or Just Inferior?

Authors
Journal
PLoS Medicine
1549-1277
Publisher
Public Library of Science
Publication Date
Volume
9
Issue
7
Identifiers
DOI: 10.1371/journal.pmed.1001240
Keywords
  • Essay
  • Medicine
  • Clinical Research Design
  • Infectious Diseases
Disciplines
  • Medicine
  • Philosophy

Abstract

Using the SWITCHMRK and MONET trials as examples, Andrew Carr and colleagues question the ethics and motives of switch or simplification trials of anti-retroviral therapy.

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