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Abdominal Bloating: Pathophysiology and Treatment

Authors
Journal
Journal of Neurogastroenterology and Motility
2093-0879
Publisher
The Korean Society of Neurogastroenterology and Motility (KAMJE)
Publication Date
Volume
19
Issue
4
Identifiers
DOI: 10.5056/jnm.2013.19.4.433
Keywords
  • Review
Disciplines
  • Biology
  • Medicine

Abstract

Abdominal bloating is a very common and troublesome symptom of all ages, but it has not been fully understood to date. Bloating is usually associated with functional gastrointestinal disorders or organic diseases, but it may also appear alone. The pathophysiology of bloating remains ambiguous, although some evidences support the potential mechanisms, including gut hypersensitivity, impaired gas handling, altered gut microbiota, and abnormal abdominal-phrenic reflexes. Owing to the insufficient understanding of these mechanisms, the available therapeutic options are limited. However, medical treatment with some prokinetics, rifaximin, lubiprostone and linaclotide could be considered in the treatment of bloating. In addition, dietary intervention is important in relieving symptom in patients with bloating.

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