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Thrombus aspiration during primary percutaneous coronary intervention leads to reduced myocardial edema and microvascular obstruction in infarct segment post acute myocardial infarction

Authors
Journal
Journal of Cardiovascular Magnetic Resonance
1097-6647
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
13
Identifiers
DOI: 10.1186/1532-429x-13-s1-p133
Keywords
  • Poster Presentation

Abstract

Thrombus aspiration during primary percutaneous coronary intervention leads to reduced myocardial edema and microvascular obstruction in infarct segment post acute myocardial infarction POSTER PRESENTATION Open Access Thrombus aspiration during primary percutaneous coronary intervention leads to reduced myocardial edema and microvascular obstruction in infarct segment post acute myocardial infarction Mohammad I Zia*, Nilesh R Ghugre, Kim A Connelly, Graham A Wright, Alexander J Dick From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. 3-6 February 2011 Introduction Thrombus aspiration has been previously shown to improve myocardial blush grade during primary percu- taneous coronary intervention (PCI) for acute myocar- dial infarction (AMI), with no impact on mortality or reinfarction. The impact of thrombus aspiration on myocardial edema and hemorrhage is unknown. Purpose Our goal was to determine the impact of thrombus aspiration during primary PCI on myocardial edema and hemorrhage post AMI. Methods Thirty-seven patients were enrolled post AMI and underwent CMR on a GE Signa Excite, 1.5T scanner with a 8-channel receive coil at 48 hours post MI. T2 maps were computed from a previously validated car- diac-gated spiral imaging sequence with T2 preparations yielding TEs=2.9,24.3,88.2,184.2 ms to assess myocardial edema. The T2* sequence was a multiecho acquisition with 8 echoes (between 1.4 and 12.7ms) acquired at TR=14.6ms. T2-weighted imaging using a breath-hold triple IR fast spin echo sequence and delayed hyperen- hancement (DHE) were also performed. We retrospec- tively stratified patients into those that had received thrombus aspiration versus not, based on the operator’s discretion. Results We compared 26 patients (mean age:59.4 years; 5 ante- rior infarcts; mean CK:2022 IU/L) that did receive thrombus aspiration versus eleven patients (mean age:58.5 years; 4 anterior infarcts; mean CK:2070 IU/L) that did not during primary PCI. The mean T2 was higher in th

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