Affordable Access

Publisher Website

A one-pot synthesis of 3-methyl-5-aryl-4H-pyrrolo[2,3-d]-isoxazoles

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
47
Issue
28
Identifiers
DOI: 10.1016/j.tetlet.2006.04.145
Keywords
  • Sharpless Epoxidation
  • Epoxide Ring-Opening
  • Cyclization
  • Dehydration
  • One-Pot Synthesis

Abstract

Abstract Sharpless epoxidation of 4-amino-3-methyl-5-styrylisoxazoles 1 resulted in the formation of 3-methyl-5-aryl-4 H-pyrrolo[2,3- d]-isoxazoles 4 in a one-step reaction. The reaction initially involves epoxide formation, followed by ring-opening and cyclization. Finally dehydration leads to the title compounds. The pyrrolo[2,3- d]-isoxazoles 4 were also synthesized via an alternative procedure.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Ferrocenylamines2. Reductive methylation of second...

on Journal of Organometallic Chem... Jan 01, 2006

3He and4He from D2absorbed in LaNi5

on Journal of Alloys and Compound... Jan 01, 1992
More articles like this..