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Selective reduction of isoxazoles with samarium diiodide

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
23
Issue
48
Identifiers
DOI: 10.1016/s0040-4039(00)85559-8

Abstract

Abstract Samarium diiodide is an efficient reagent for the reductive cleavage of the ON bond of isoxazoles. Olefins, esters, and acetals are stable to the reaction conditions, benzylic halides and aldehydes are not.

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