Purpose To compare the outcomes between implantable collamer lenses (ICLs), 1 with and 1 without a central artificial hole. Design Comparative study. Methods We included 65 eyes of 65 patients with refractive error in our study. The mean manifest refraction spherical equivalent (MRSE) was −9.32 ± 4.02 diopters (range, 6.75 to −16.50 diopters). We divided patients into 2 groups based on the type of ICL used, 1 for those without a central artificial hole (Group I, 21 eyes) and 1 for those with a hole (Group II, 44 eyes). The postoperative changes in visual acuity, endothelial cell density, MRSE, higher order aberrations readings, and objective scatter index between the 2 kinds of ICLs were compared. The follow-up period was 3 months. Results There were no statistically significant differences in the postoperative changes in uncorrected distance visual acuity (P = 0.81), corrected distance visual acuity (P = 0.24), MRSE (P = 0.18), and endothelial cell density (P = 0.76) between the groups. Also, no difference in objective scatter index was found at 3 months (P = 0.32). None of the higher order aberrations readings showed any significant difference between the groups. Conclusion There were no significant differences between the outcomes of these ICLs, either with or without a central artificial hole.