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Some progress in the use of a scanning transmission electron microscope for the observation of biomacromolecules

Authors
Journal
Journal of Ultrastructure Research
0022-5320
Publisher
Elsevier
Publication Date
Volume
57
Issue
3
Identifiers
DOI: 10.1016/s0022-5320(76)80120-7
Disciplines
  • Biology

Abstract

A new scanning transmission electron microscope equipped with an efficient dark-field detector is used to visualize biological specimens chosen among those best suitable for high resolution conventional electron microscopy. Micrographs of stacked-disk aggregates of tobacco mosaic virus protein, type I pili of Escherichia coli, DNA, and chromatin beads are presented. They compare favorably with the best images obtained to date with conventional electron microscopy.

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