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Calcitonin gene-related peptide innervation of A2-catecholamine cells in the nucleus of the solitary tract of the rat

Authors
Journal
Brain Research
0006-8993
Publisher
Elsevier
Publication Date
Volume
690
Issue
1
Identifiers
DOI: 10.1016/0006-8993(95)00639-8
Keywords
  • Calcitonin Gene-Related Peptide
  • Tyrosine Hydroxylase
  • Double Immunohistochemistry
  • Nucleus Of The Solitary Tract
  • A2-Catecholaminergic Cell Group

Abstract

Abstract By using double immunolabeling light and electron microscopic techniques, dense neuronal network of calcitonin gene-related peptide (CGRP) has been visualized in the nucleus of the solitary tract with complete overlapping of the tyrosine hydroxylase (TH)-containing cells. TH-immunoreactive perikarya and dendrites were seen in synaptic contact with CGRP-immunopositive fibers, indicating that CGRP, by carrying sensory signals may influence autonomic regulatory mechanisms in the NTS through local catecholaminergic neurons.

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