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Conicamin, a novel histamine antagonist from the mediterranean tunicateAplidium conicum

Authors
Journal
Bioorganic & Medicinal Chemistry Letters
0960-894X
Publisher
Elsevier
Publication Date
Volume
13
Issue
24
Identifiers
DOI: 10.1016/j.bmcl.2003.08.081

Abstract

Abstract In addition to the known 6-bromo-hypaphorine ( 2) and plakohypaphorine-A ( 3), the methanol extract of the Mediterranean tunicate Aplidium conicum was shown to contain conicamin, a novel indole alkaloid having histamine-antagonistic activity which structure was determined to be 1 on the basis of the spectral data.

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