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Pre-induction cervical ripening: A randomized comparison of two methods

Authors
Journal
Obstetrics and Gynecology
0029-7844
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Volume
85
Issue
4
Identifiers
DOI: 10.1016/0029-7844(95)00013-h

Abstract

Objectives To compare two methods of pre-induction cervical ripening in a randomized clinical trial. Methods A single intracervical prostaglandin E 2 (PGE 2) gel application was compared with a single insertion of hygroscopic dilators in 441 women at term with unfavorable cervical scores. Induction success was defined as entry into active labor within 6 hours of oxytocin infusion. Results There was no statistical difference in pre- or post-ripening cervical scores. In the group receiving hygroscopic dilators, only 28% entered the active phase of labor within 6 hours of oxytocin infusion compared with 45% ( P < .001) in the PGE 2 group. Thus, in this study, a change in cervical score did not directly predict induction success. There was a higher rate of postpartum endometritis (24 versus 14%; P =.007) and suspected neonatal infection (10 versus 5%; P =.03) in the dilator group..001) in the PGE 2 group. Thus, in this study, a change in cervical score did not directly predict induction success. There was a higher rate of postpartum endometritis (24 versus 14%; P =.007) and suspected neonatal infection (10 versus 5%; P =.03) in the dilator group..001) in the PGE 2 group. Thus, in this study, a change in cervical score did not directly predict induction success. There was a higher rate of postpartum endometritis (24 versus 14%; P =.007) and suspected neonatal infection (10 versus 5%; P =.03) in the dilator group. Conclusions Pre-induction ripening by hygroscopic dilators and intracervical PGE 2, was equivalent as measured by changes in the cervical score. The change in cervical score, however, was not predictive of successful induction, and PGE 2, was more frequently associated with induction success. Hygroscopic dilators were associated with a higher incidence of postpartum maternal and neonatal infection because of a longer duration of labor. Hospital charges for intracervical PGE 2, gel totaled $522 compared with $91 for the insertion of three dilators.

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