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A review of the health consequences of the vitamin D deficiency pandemic

Authors
Journal
Journal of the Neurological Sciences
0022-510X
Publisher
Elsevier
Publication Date
Volume
311
Identifiers
DOI: 10.1016/j.jns.2011.08.046
Keywords
  • 25-Hydroxyvitamin D
  • Extraskeletal Effects
  • Mortality
  • Infections
  • Cancer
Disciplines
  • Biology
  • Medicine

Abstract

Abstract Rickets, osteomalacia, osteoporosis and myopathy are among the better known consequences of a low to very low vitamin D status. Over the past several years various predominantly epidemiological and prospective cohort studies have found associations between low vitamin D levels and various extraskeletal conditions. These findings may particularly become important over the next years since large proportions of the population have low vitamin D levels. Increasing incidence rates of obesity, adverse life-style factors and active avoidance of sunlight seem to decrease average population mean vitamin D levels further. This article gives a brief overview of known and also less well-established potential detrimental effects of a low vitamin D status.

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