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Ising model forB-Ztransition in supercoiled DNA

Authors
Journal
Bulletin of Mathematical Biology
0092-8240
Publisher
Springer-Verlag
Publication Date
Volume
54
Issue
5
Identifiers
DOI: 10.1016/s0092-8240(05)80140-5
Disciplines
  • Chemistry

Abstract

The possible existence of nucleic acids in right-handed and left-handed helical forms is considered. A statistical mechanical model is developed to obtain an expression for a change in twist during helical transformation in terms of corresponding free energies and linking for a supercoiled DNA. The theoretically predicted values are compared with those determined experimentally. The physico-chemical significance of the parameters is discussed.

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