Based on the emerging literature on positivity in behavioural and organizational sciences, this thesis conceptualizes the phenomenon of Vitality at Work (VAW). The concept is based on the interdependence of individual and organizational health which exist in a symbiotic relationship. VAW is an integrative, over-arching framework combining individual health and well-being with positive work attitudes and positive social interactions. These have not been brought together within a single construct in the literature. The thesis also explores the concept of Subjective Career Plateau (SCP), a subjective state where an individual believes that the probability of future career advancement, both in terms of hierarchical progression and lateral diversification are low. Data are presented which examine the effect of Subjective Career Plateau on Vitality at Work. The study presents data from the UK Higher Education Sector with responses collected from academics working in top-ranking UK universities. The study employs a survey methodology and quantitative methods for data analysis. Using 365 valid responses, the study validates the concept of Vitality through Exploratory Factor Analysis and Confirmatory Factor Analysis. Confirmatory Factor Analysis confirms a clear structure of the suggested factors and validates the measurement model for Vitality. A measurement model is also confirmed for measuring Subjective Career Plateau through CFA. Regression analysis is employed to test the hypothesis between SCP and VAW and the results confirm that Subjective Career Plateau has a significant effect on Vitality. The thesis makes a contribution to theory and knowledge by developing an important organizational concept and exploring its relationship with Subjective Career Plateau. Based on the findings, recommendations are offered to managers, practitioners and policy-makers for an increased focus on individual health and well-being, development of a positive and energizing work environment and provision of opportunities for career development and diversification. Finally, the thesis discusses the possible future opportunities for research.