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Malignant Melanoma Occurring Within a Previously Irradiated Area

Authors
Journal
Clinical Oncology
0936-6555
Publisher
Elsevier
Volume
11
Issue
6
Identifiers
DOI: 10.1053/clon.1999.9100
Keywords
  • Malignant Melanoma
  • Radiation-Induced Neoplasia
Disciplines
  • Medicine

Abstract

Abstract The commonest radiation-induced neoplasms are sarcomas. Ionizing radiation is not usually associated with the development of malignant melanoma. We report two patients with malignant melanoma occurring within a previously irradiated area. There is evidence to support radiation in the pathogenesis of melanoma but the family histories, especially in one patient, suggest that genetic mutations may also have played a role, particularly in relation to the short latent period.

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