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Retinopathy and microalbuminuria in type II diabetic patients

BioMed Central
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  • Research Article
  • Medicine

Abstract ral ss BioMed CentBMC Ophthalmology Open AcceResearch article Retinopathy and microalbuminuria in type II diabetic patients Masoud R Manaviat*, Mohammad Afkhami and Mohammad R Shoja Address: Diabetes Research Center, Jomhoori Blvd, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Email: Masoud R Manaviat* - [email protected]; Mohammad Afkhami - [email protected]; Mohammad R Shoja - [email protected] * Corresponding author Abstract Background: The aim of this study was to identify risk factors for the development of retinopathy and microalbuminuria and their correlation in type II diabetic patients. Methods: In this cross-sectional study 590 patients suffering from diabetis type II were examined. Fundoscopy was performed by practising ophthalmologist. The ratio of urinary albumin to creatinine was assessed by clinitek 100 (Bayer corporation–USA). HbA1C, height and weight also were measured. Results: The overall prevalence of retinopathy was 39.3% (232 patients), 5.4% of which showed to be prolifrative diabetic retinopathy (PDR). The diabetic retinopathy had significant inverse correlation with body mass index (BMI) (P = 0.02). HbA1C was higher in patients with PDR (mean = 10.5%) than in patients with no signs of retinopathy (mean = 9.5%) and this difference was statistically significant (P = 0.001). The prevalence of microalbuminuria was 25.9% while 14.5% of the patients revealed to have macroalbuminuria. As expected, diabetic retinopathy and renal involvement were highly positively correlated. (P = 0.001). Conclusion: Microalbuminuria is associated with diabetic retinopathy in type II diabetic patients and is a reliable marker of retinopathy. Background Diabetes mellitus is one of the most common metabolic diseases in which either the hormone insulin is lacking or the body's cells are insensitive to insulin effects. The multi-system effects of diabetes such as retinopathy, nephropathy, neuropathy and cardiovascular diseases are cons

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