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Immunological unresponsiveness in the rat to cestode antigens

Authors
Journal
Experimental Parasitology
0014-4894
Publisher
Elsevier
Publication Date
Volume
19
Issue
1
Identifiers
DOI: 10.1016/0014-4894(66)90049-x
Disciplines
  • Biology
  • Medicine

Abstract

Abstract Neonatal injections of 10,000 gamma of Echinococcus granulosus cyst fluid protein or Taenia hydatigena cysticercus fluid protein induced immunological unresponsive states (tolerance) to these antigens in Wistar albino rats. Unresponsiveness to the two helminth fluids was reciprocal, specific, and of finite duration. The tolerant states could be terminated by injections of the tolerance inducing antigens in Freund's complete adjuvant.

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