Affordable Access

Publisher Website

PROBABLE IDENTIFICATION OF AN HL-A SECOND-LOCUS ANTIGEN ASSOCIATED WITH A HIGH RISK OF NASOPHARYNGEAL CARCINOMA

Authors
Journal
The Lancet
0140-6736
Publisher
Elsevier
Publication Date
Volume
305
Issue
7899
Identifiers
DOI: 10.1016/s0140-6736(75)91433-6

Abstract

Abstract An HL-A antigen profile comprising an increased frequency of HL-A2 and undetectable second-locus antigen(s) in Chinese patients with nasopharyngeal carcinoma (N.P.C.) has been reported. To investigate whether the deficit of second-locus antigen(s) had a genetic basis, sera from parous women in Singapore were screened for anti- HL-A activity corresponding to the second-locus "blank". A second-locus (Singapore-2) was identified which seems to be associated with a high risk of N.P.C.

There are no comments yet on this publication. Be the first to share your thoughts.