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The Ah Locus: Biochemical Basis for Genetic Differences in Brain Tumor Formation in Mice

Authors
Journal
Genetics
0016-6731
Publisher
The Genetics Society of America
Publication Date
Keywords
  • Investigations

Abstract

Allelic differences at the Ah locus are shown to exist in the mouse brain. This finding probably explains inbred mouse strain differences in polycyclic hydrocarbon tumorigenesis of the brain described more than 35 years ago and may be important in understanding the etiology of genetic differences in certain human intracranial neoplasms.

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