Conjugated Linoleic Acids Reduce Body Fat in Healthy Postmenopausal Women

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Conjugated Linoleic Acids Reduce Body Fat in Healthy Postmenopausal Women

Authors
Publisher
American Society for Nutrition
Keywords
  • J
  • Parallel
  • Leptin
  • In This Study
  • 0
  • 2009
  • In Conclusion
  • 04)
  • Respectively)
  • T11- And T10
  • 001
  • In Humans
  • Isomers Of Conjugated Linoleic Acids (Cla) Reduce Fat Mass Fm) And Increase Insulin Sensitivity In S
  • But Not All
  • Murine Studies
  • This Effect Is Still Debatable
  • We Compared The Effect Of 2 Cla Supplements On Total And Regional Fm Assessed By Dual Energy X-Ray A
  • Changes In Serum Insulin And Glucose Concentrations
  • And Adipose Tissue (At) Gene Expression In Humans
  • In A Double-Blind
  • 16-Wk Intervention
  • We Randomized 81 Healthy Postmenopausal Women To 1) 5
  • 5 G/D Of 40/40% Of Cis9
  • Trans11-Cla (C9
  • T11-Cla) And Trans10
  • Cis12-Cla (T10
  • C12-Cla) (Cla-Mix)
  • 2) Cis9
  • T11-Cla)
  • Or 3) Control (Olive Oil)
  • We Assessed All Variables Before And After The Intervention
  • The Cla-Mix Group Had Less Total Fm (4%) And Lower-Body Fm (7%) Than The Control (P = 0
  • 02 And &Lt
  • Post Hoc Analyses Showed That Serum Insulin Concentrations Were Greater In The Cla-Mix Group (34%) T
  • 02) In The Highest Waist Circumference Tertile Only
  • At Mrna Expression Of Glucose Transporter 4
  • And Lipoprotein Lipase Was Lower
  • Whereas Expression Of Tumor Necrosis Factor-Alpha Was Higher In The Cla-Mix Group Than In The Contro
  • A 50:50 Mixture Of C9
  • C12-Cla Isomers Resulted In Less Total And Lower-Body Fm In Postmenopausal Women And Greater Serum I
  • Future Research Is Needed To Confirm The Insulin Desensitizing Effect Of The Cla Mixture And The Eff
  • Nutr
  • 139: 1347-1352

Abstract

Conjugated Linoleic Acids Reduce Body Fat in Healthy Postmenopausal Women - DTU Orbit (15/04/14) Conjugated Linoleic Acids Reduce Body Fat in Healthy Postmenopausal Women - DTU Orbit (15/04/14) Raff M, Tholstrup T, Toubro S, Bruun JM, Lund P, Straarup EM et al. Conjugated Linoleic Acids Reduce Body Fat in Healthy Postmenopausal Women. Journal of Nutrition. 2009;139(7):1347-1352. Available from: 10.3945/jn.109.104471

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