Abstract 1. 1. A brief review of the literature on human bites is presented, with special notice of literature of the antibiotic era. 2. 2. Forty-four cases of human bites seen at the Detroit Receiving Hospital are presented and data tabulated. Seven cases are presented in more detail, with x-rays and photographs. 3. 3. Cultures on eight cases with sensitivities on five of these are tabulated. 4. 4. Discussion of trends and special features of the series is presented. 5. 5. An outline of treatment based on our observations is given.