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Neuropeptide processing enzymes

Authors
Journal
Trends in Neurosciences
0166-2236
Publisher
Elsevier
Publication Date
Volume
7
Issue
7
Identifiers
DOI: 10.1016/s0166-2236(84)80219-2
Disciplines
  • Biology

Abstract

Neuropeptides are synthesized as part of a larger, sometimes much larger precursor molecule, which may contain a variety of other active peptides. These precursors are cleaved, often at sites flanked by the basic amino-acids, arginine and lysine, and selective processing may play an important role in determining which peptides are finally released by the cell. This article reviews the selectivities of the various enzymes known to play a role in neuropeptide processing.

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