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Enhancement of formation of the initiation complex by a factor stimulating RNA polymerase II from Ehrlich ascites tumor cells

Authors
Journal
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis
0005-2787
Publisher
Elsevier
Publication Date
Volume
479
Issue
2
Identifiers
DOI: 10.1016/0005-2787(77)90138-1
Disciplines
  • Biology

Abstract

Abstract A method was developed for measuring formation of the initiation complex in a eucaryotic transcription system. A factor stimulating RNA polymerase II from Ehrlich ascites tumor cells was found to enhance formation of the initiation complex with RNA polymerase II and homologous DNA. This enhancement was not due to modification of the enzyme or template DNA by this factor.

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