Abstract Alkali-activated slag-fly ash cementitious material system (CMS-ASF) was prepared by using NaOH (NH), Na 2CO 3 (NC) as alkali-activator and slag, fly ash as composite material. The basic characteristics, including temperature-stimulating, strength, setting and hardening, application, of CMS-ASF were systematically studied based on the paste specimen. The results showed that the rheological characterization and mechanical properties were sensitive to the change of alkali-activator temperature. Reliable strength system that endures the examination of practice was established by Response Surface Methodology, the strength system can provide a direction for practical application and used in developing theory research. When alkali-activator temperature is 40 °C, the setting time conformed to the requirements of national standard. CMS-ASF has following application characteristics: simple manufacturing technique, low cost in production, eco-friendly. So CMS-ASF has a series of excellent characteristics, there is a bright future development prospect.