Affordable Access

Publisher Website

Origin and termination of dorsal raphe-median eminence projection

Authors
Journal
Brain Research
0006-8993
Publisher
Elsevier
Publication Date
Volume
324
Issue
1
Identifiers
DOI: 10.1016/0006-8993(84)90637-1
Keywords
  • Dorsal Raphe Nucleus
  • Median Eminence
  • Serotonergic Innervation
  • Serotonin

Abstract

Abstract The origin and termination of the dorsal raphe (DR)-median eminence (ME) projection were studied by combining well-limited small electrolytic lesions of different parts of the DR, the axonal degeneration and the serotonin content in the median eminence. Our results show that the rostral third of the DR is a source of serotonergic innervation to the ME and that the rest of the nucleus does not contribute to this projection. The light microscopy study revealed that degenerating fibers occupy the internal layer of the ME. Those results were confirmed by electron microscopy which in addition showed degenerating terminals.

There are no comments yet on this publication. Be the first to share your thoughts.