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Archaeal Protein Biogenesis: Posttranslational Modification and Degradation

Hindawi Publishing Corporation
Publication Date
DOI: 10.1155/2010/643046
  • Editorial
  • Biology


Hindawi Publishing Corporation Archaea Volume 2010, Article ID 643046, 2 pages doi:10.1155/2010/643046 Editorial Archaeal Protein Biogenesis: Posttranslational Modification and Degradation Jerry Eichler,1 Julie Maupin-Furlow,2 and Joerg Soppa3 1 Department of Life Sciences, Ben-Gurion University of the Negev, Beersheva, Israel 2 Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA 3 Institute for Molecular Biosciences, Frankfurt University, 60325 Frankfurt, Germany Correspondence should be addressed to Jerry Eichler, [email protected] Received 1 August 2010; Accepted 1 August 2010 Copyright © 2010 Jerry Eichler et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The study of Archaea at the DNA and RNA levels has provided considerable insight into replication, transcription, and other information-associated events which are either unique to this remarkable group of organisms or which were later found to also occur in Bacteria and/or Eukarya. In contrast, largely due to a lack of suitable model systems and a limited number of appropriate molecular tools, considerably less was known about archaeal proteins in terms of their biogenesis, modification, trafficking, or degradation. In recent years, however, we have witnessed major advances in proteomics, successful in vitro reconstitutions, and the development of reporter systems compatible with extreme conditions. Relying on such tools, insight into different stages in the life of archaeal proteins has begun to accumulate. In this special issue of Archaea, we present a series of articles addressing the current state of understanding of selected facets of archaeal protein biogenesis and process- ing. An article by De Koning et al. discussing how fidelity in archaeal information processing at the DNA, RNA, and prote

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