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Distinguishing in vitro electrochemical signatures for norepinephrine and dopamine

Authors
Journal
Neuroscience Letters
0304-3940
Publisher
Elsevier
Publication Date
Volume
95
Identifiers
DOI: 10.1016/0304-3940(88)90670-2
Keywords
  • Electrochemical Signature
  • Norepinephrine
  • Dopamine
Disciplines
  • Chemistry

Abstract

Abstract An electrochemical method for the qualitative detection of dopamine and norepinephrine in the presence of serotonin and other purported contaminants in vitro is described. The method uses semidifferential electrochemistry in conjunction with a stearate graphite paste electrode. A method to distinguish electrochemical signatures for specific catecholamines is particularly important because catecholamines are known to have similar oxidation potentials for electrochemical detection. The findings may bear relevance to the interpretation of electrochemical signals from discrete brain nuclei in vivo.

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