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The effect of low doses of fluoride on tissue enzyme activity in the rat

Authors
Journal
Archives of Oral Biology
0003-9969
Publisher
Elsevier
Publication Date
Volume
21
Issue
7
Identifiers
DOI: 10.1016/0003-9969(76)90010-8

Abstract

Abstract Although serum alkaline phosphatase activity decreased in rats given drinking water containing 10 ppm fluoride over 6 weeks, no significant change in activity was observed in liver or intestinal tissue. Acid phosphatase, glutamic oxalacetic transaminase, glutamic pyruvic transaminase and leucine aminopeptidase activities showed no significant changes in serum, liver, kidney or intestine.

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