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The pH dependence of the mutagenicity of methyl benzimidazol-2-yl carbamate (MBC) towardsAspergillus nidulans(Eidam) Winter andCladosporium cucumerinumEllis & Arth.

Authors
Journal
Mutation Research/Genetic Toxicology
0165-1218
Publisher
Elsevier
Publication Date
Volume
88
Issue
1
Identifiers
DOI: 10.1016/0165-1218(81)90089-6
Disciplines
  • Chemistry

Abstract

Abstract The ability of methyl benzimidazol-2-yl carbamate (MBC) to induce point mutations to carboxin and MBC resistance in Aspergillus nidulans (Eidam) Winter and Cladosporium cucumerinum Ellis & Arth. was dependent upon the pH value of the agar medium into which it had been incorporated. The relevance of this in relation to testing chemicals for a possible mutagenic activity with microorganisms is discussed.

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