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Modifications of histone cores and tails in V(D)J recombination

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BioMed Central
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PMC
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Abstract

A recent study shows that methylated lysine 79 in the core region of histone H3 plays a role in regulating the rearrangement of V, D and J gene segments by providing a euchromatic 'mark' that may regulate access of the V(D)J recombinase.

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