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Barium ions block the acetylcholine evoked slow H-response in the neurones ofHelix PomatiaL.

Authors
Journal
Neuroscience Letters
0304-3940
Publisher
Elsevier
Publication Date
Volume
13
Issue
2
Identifiers
DOI: 10.1016/0304-3940(79)90044-2

Abstract

Abstract The effects of barium ions on slow acetylcholine (Ach) H receptor activated hyperpolarization has been studied. The results provide evidence of a sensitive and reversible blocking action of Ba 2+ on the involved potassium conductance. 3-Aminopyridine (3-AP) also attenuated the slow H-response by 50%, showing partial effectiveness. TEA + sensitively inhibited the Ach evoked hyperpolarization interacting with the receptors.

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