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Neuron-specific enolase: investigation on its possible retrogade axonal transport

Authors
Journal
Brain Research
0006-8993
Publisher
Elsevier
Publication Date
Volume
291
Issue
1
Identifiers
DOI: 10.1016/0006-8993(84)90668-1
Keywords
  • Neuron-Specific Enolase
  • Retrograde Axonal Transport
  • Radioimmunoassay
Disciplines
  • Biology

Abstract

Abstract The possible rapid retrograde axonal transport of neuron-specific enolase was investigated employing a sensitive radioimmunoassay. The right sciatic nerve of rats was ligated and 6 and 24 h later the nerve was cut in two 5.0 mm segments immediately proximal and distal to the ligature. Similar were taken from the contralateral nerve as a control. No increase in the amount of neuron-specific enolase in the right-distal segment was observed indicating that the protein is not a component of retrograde axonal transport.

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