Affordable Access

Ultrafast enzymatic reaction dynamics in protochlorophyllide oxidoreductase.

Authors
Journal
Nautre Structural Biology
1072-8368
Publisher
Nature Publishing Group
Publication Date
Disciplines
  • Biology

Abstract

The reaction catalyzed by the light-driven enzyme protochlorophyllide oxidoreductase (POR) has been initiated with a 50-fs laser pulse. We show that the catalytic mechanism, involving proton and hydride transfers, proceeds with time constants of 3 ps and 400 ps. It is known that catalysis by POR involves thermally excited protein dynamics; our results show that these molecular motions occur on an ultrafast timescale.

There are no comments yet on this publication. Be the first to share your thoughts.