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Distinctive antibody responses induced by immunization of mice with rat monoclonal antibodies specific for a panel of dendritic cell surface markers

Academic Medical Center, University of Amsterdam
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  • Medicine


LC2013 -- Cover -- Front 2013LC 13th International Workshop on Langerhans Cells October 10 -13, 2013 Amsterdam, The Netherlands SCIENTIFIC PROGRAM & ABSTRACTS 1 WELCOME Ladies and gentlemen, friends and colleagues, Langerhans researchers all over the world, The fact that the Nobel Prize in Medicine 2011 was awarded to Ralph M. Steinman "for his discovery of the dendritic cell and its role in adaptive immunity" underlines the importance of dendritic cells. Dendritic cells, including epidermal skin Langerhans cells are considered to be master regulators for protective immunity and tolerance. Langerhans cell research is an established niche within research on dendritic cells, encompassing both fundamental and clinical immunology. The development of exiting new experimental models boosted interest in skin dendritic cells, also including dermal dendritic cells. All basic research on Langerhans cells and dermal dendritic cells over the last decades is beginning to pay off, as clinical opportunities become clear, such as intradermal vaccination. The tradition of having biennial International Langerhans Cell Workshops started in 1989 in Oslo, Norway, and we are happy to host the 13th workshop in Amsterdam. The rich cultural background of the capital city of The Netherlands, together with its many social opportunities, guarantees a successful meeting and the initiation of new collaborations and interactions between advanced and young researchers but also between researchers and industry. LC2013 will focus on the function of Langerhans cells and other dendritic cell subsets in skin and mucosa. The recent developments in the field will be highlighted with excellent invited speakers, state‐of‐the art oral presentations and poster sessions. We cordially invite researchers, dermatologists, and industry to actively participate and interact in the 13th International Workshop on Langerhans Cells in Amsterdam, The Netherlands. LC2013 provides the

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