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Neomycin production with free and immobilized cells ofStreptomyces marinensisin an airlift reactor

Authors
Journal
Process Biochemistry
1359-5113
Publisher
Elsevier
Publication Date
Volume
38
Issue
4
Identifiers
DOI: 10.1016/s0032-9592(02)00182-6
Keywords
  • Bioreactor
  • Immobilization
  • Neomycin
  • Streptomyces Marinensis

Abstract

Abstract Neomycin production by free and alginate immobilized Streptomyces marinensis cells was investigated in an airlift reactor. Neomycin production was increased two and a half times with immobilized cells. A marginal decrease in neomycin production was noticed with reduced supplementation of carbon source (up to one-fourth concentration). Immobilized S. marinensis particles showed a half-life of 20 days during continuous fermentation in an airlift reactor.

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