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A Case Report of Anesthetic Management for a Patient with a Family History of Operative Death due to Malignant Hyperthermia

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  • Medicine


We successfully anesthetized a patient whose cousin had died of malignant hyperthermia (MH) perioperatively. The patient was a 41 years old man who underwent transuretheral ureterolithotomy. We carefully selected anesthetic methods (spinal anesthesia) and monitored respiratory and circulatory status intraoperatively. The surgery was uneventful. We opted to forgo the "calcium induced calcium release (CICR)" preoperatively, though it was an important diagnostic test for MH, because (1) there was no history of abnormal body temperature or neuro-muscular disease, (2) genetically, the relation between this patient and the cousin who had died of MH was sufficiently distant that the risk of MH was relatively low and he didn't desire CICR.

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