In order to investigate the blood pressure and heart rate responses to a standard lower limb isokinetic test, 19 subjects between the ages of 20 and 30 were measured prior to, immediately post-exercise, and for four minutes into recovery. Although no direct comparisons were available, these values were found to reflect cardiovascular responses consistent with those seen in maximal treadmill testing. In addition, correlation studies demonstrated a nonsignificant relationship between systolic blood pressure and heart rate at all stages. Similarly, no significant relationship was found using scales of distress or perceived exertion. The implications of these findings are discussed in conjunction with relevant cardiovascular stress testing literature. Clinical recommendations include the implementation of a standardised screening procedure, a supervised cool-down phase and standard stress-testing precautions when undertaking maximal isokinetic testing.