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Recruitment of proteins to modulate protein-protein interactions

Authors
Publisher
Elsevier Ltd
Publication Date
Volume
6
Issue
8
Identifiers
DOI: 10.1016/s1074-5521(99)80080-5
Disciplines
  • Biology
  • Medicine

Abstract

Abstract The use of a ‘borrowed’ protein surface to either enhance or inhibit the interaction of a small ligand with its protein target has been reported recently. This approach represents a general method for modulating protein-protein interactions and may find many applications in both biology and medicine.

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