Affordable Access

Publisher Website

Proton radiography for clinical applications

Authors
Journal
Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment
0168-9002
Publisher
Elsevier
Publication Date
Volume
612
Issue
3
Identifiers
DOI: 10.1016/j.nima.2009.08.040
Keywords
  • Proton Radiation Therapy
  • Proton Computed Tomography
  • Proton Radiography
  • Image Reconstruction
  • Particle Calorimetry
  • Position Sensitive Particle Detectors
  • Proton Beams
Disciplines
  • Medicine

Abstract

Abstract Proton imaging is not yet applied as a clinical routine, although its advantages have been demonstrated. In the context of quality assurance in proton therapy, proton images can be used to verify the correct positioning of the patient and to control the range of protons. Proton computed tomography (pCT) is a 3D imaging method appropriate for planning and verification of proton radiation treatments, because it allows evaluating the distributions of proton stopping power within the tissues and can be directly utilized when the patient is in the actual treatment position. The aim of the PRoton IMAging experiment, supported by INFN, and the PRIN 2006 project, supported by MIUR, is to realize a proton computed radiography (pCR) prototype for reconstruction of proton images from a single projection in order to validate the technique with pre-clinical studies and, eventually, to conceive the configuration of a complete pCT system. A preliminary experiment performed at the 250 MeV proton synchrotron of Loma Linda University Medical Center (LLUMC) allowed acquisition of experimental data before the completion of PRIMA project's prototype. In this paper, the results of the LLUMC experiment are reported and the reconstruction of proton images of two phantoms is discussed.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Proton radiography applications with MCNP5.

on Radiation Protection Dosimetry 2005

Clinical applications of radiography and ancillary...

on The Veterinary clinics of Nort... March 1996
More articles like this..