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Unnatural oligomers and unnatural oligomer libraries

Authors
Journal
Current Opinion in Chemical Biology
1367-5931
Publisher
Elsevier
Publication Date
Volume
1
Issue
1
Identifiers
DOI: 10.1016/s1367-5931(97)80118-4
Disciplines
  • Mathematics

Abstract

Abstract Within the past few years, a variety of compounds that mimic biopolymers have been developed. All of these unnatural oligomers are prepared by iterative syntheses, which are amenable to combinatorial strategies. Peptides continue to be popular targets for mimicry, and there is growing interest in targeting oligosaccharides. The incorporation of unnatural oligomers into compounds that adopt defined structures, such as helices or sheets, has emerged as an exciting new area of unnatural oligomer research.

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