Abstract The healing of small adipose tissue implants was evaluated in experimental studies on rats. Adipose tissue of approximately 0.5 ml volume was obtained by resection of parauterine fat pads. The tissue was divided into fragments that were 1–3 mm in size and implanted under the dorsal skin. The implantation of adipose tissue in fragments offered no biological advantage and the healing process terminated in extensive necrosis of fat cells. The results are analysed and considered in relation to the implantation of adipose tissue fragments obtained by liposuction.