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A rapid technique for visualizing cerebral arteries in rat

Authors
Journal
Behavioral and Neural Biology
0163-1047
Publisher
Elsevier
Publication Date
Volume
58
Issue
3
Identifiers
DOI: 10.1016/0163-1047(92)90552-f
Disciplines
  • Biology
  • Medicine

Abstract

Intracardiac perfusion with cresyl violet acetate dissolved in 0.9% isotonic saline and dimethyl sulfoxide (DMSO) allows one to visualize the arterial blood supply to the central hemispheres. This technique is especially useful in demonstrating the ramifications of and areas supplied by the middle cerebral artery. Many individual differences in the course traversed by the artery and the distal areas supplied were observed. This technique could prove to be a useful adjunct to neurohistological techniques in studies investigating rodent models of stroke.

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