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Analytical methods applied to the determination of heterocyclic aromatic amines in foods

Authors
Journal
Journal of Chromatography B
1570-0232
Publisher
Elsevier
Publication Date
Volume
862
Identifiers
DOI: 10.1016/j.jchromb.2007.11.040
Keywords
  • Heterocyclic Aromatic Amines
  • Foods
  • Extraction Methods
  • Chromatographic Methods/Mass Spectrometry
  • Capillary Electrophoresis

Abstract

Abstract Analytical aspects concerning the heterocyclic aromatic amines (HAAs) determination in foods are reviewed. Sample pre-treatment procedures such as liquid–liquid extraction (LLE), supercritical fluid extraction, solid-phase extraction (SPE), solid-phase microextraction (SPME), and the mainly used LLE–SPE tandem extraction are discussed. The analytical methods used for the identification and quantification are HPLC, HPLC combined with single or tandem MS detection (HPLC-MS, HPLC-MS/MS), GC–MS and capillary electrophoresis. Advantages and figures of merit for each technique are discussed.

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