Affordable Access

Publisher Website

The effect of intracellular current pulses on membrane potentials in the moth heart

Authors
Journal
Comparative Biochemistry and Physiology
0010-406X
Publisher
Elsevier
Publication Date
Volume
17
Issue
2
Identifiers
DOI: 10.1016/0010-406x(66)90590-1

Abstract

Abstract 1. 1. A single microelectrode was used for simultaneously passing current pulses and recording bioelectric activity in single cells of the moth heart. 2. 2. The cell membrane responds to depolarizing and hyperpolarizing pulses as an ohmic resitor, showign no rectification with current flows up to 5 × 10 −9 A. 3. 3. A polarization resistance of 3.8±1 MΩ was measured and a specific membrane resistance of 1360Ω cm 2 was calculated. 4. 4. Action potential height was attenuated by depolarization and augmented by hyperpolarization. 5. 5. Although the slope of the prepotential declined in response to depolarizing pulses and increased in response to hyperpolarizing pulses, the rhythm of the spontaneous beat was not altered. 6. 6. The average rate of fall of the action potential was increased by hyper- polarization and diminished so markedly by depolarization that a plateau phase appeared where none had previously been detectable. The initial rising phase and the falling phase of the action potential could thus be altered by manipulating the membrane voltage.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Effects of membrane current on transmembrane poten...

on The American journal of physio... October 1959

THE EFFECT OF ANION SUBSTITUTION ON BIOELECTRIC PO...

on Comparative biochemistry and p... October 1964

The effect of anion substitution on bioelectric po...

on Comparative Biochemistry and P... Jan 01, 1964

Effects of Cyclopiazonic Acid on Membrane Currents...

on Journal of Molecular and Cellu... Jan 01, 1995
More articles like this..