Affordable Access

Publisher Website

Cutaneous lesions of disseminated histoplasmosis in human immunodeficiency virus-infected patients

Authors
Journal
Journal of the American Academy of Dermatology
0190-9622
Publisher
Elsevier
Publication Date
Volume
23
Issue
3
Identifiers
DOI: 10.1016/0190-9622(90)70235-a
Disciplines
  • Biology
  • Medicine

Abstract

Disseminated histoplasmosis is being diagnosed more frequently in persons infected with the human immunodeficiency virus and is often the initial manifestation of the acquired immunodeficiency syndrome (AIDS). Disease-related cutaneous features of HIV-associated disseminated histoplasmosis are denned as mucocutaneous lesions from which fungal organisms were either cultured or demonstrated histopathologically. We report four HIV-seropositive patients with disseminated histoplasmosis who had culture-positive skin or oral lesions of histoplasmosis and review the specific cutaneous manifestations of HIV-associated disseminated histoplasmosis. Including our patients, disease-related sMn and/or mucosal lesions were present in 11% of patients (26% of 239) with HIV-associated disseminated histoplasmosis. The possibility of disseminated histoplasmosis should be considered in all HIV-infected persons and in persons with AIDS risk factors who have fever, weight loss, hepatosplenomegaly, and new cutaneous lesions. An early skin or mucosal biopsy specimen for crushed tissue preparation, histologic evaluation, and fungal culture is a simple, rapid diagnostic procedure.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Cutaneous lesions of disseminated histoplasmosis i...

on Journal of the American Academ... September 1990

Disseminated cutaneous histoplasmosis in patients...

on Journal of Cutaneous Pathology April 2002

Disseminated histoplasmosis in patients infected w...

on Clinical Infectious Diseases March 1992

Clinicopathological features of cutaneous histopla...

on Transactions of the Royal Soci... Jan 01, 2001
More articles like this..