Abstract Excitation functions for the reactions 107Ag(α,n) 110In, 107Ag(α,2n) 109In, 109Ag(α,2n) 111In, 109Ag(α,3n) 110In and 109Ag(α,4n) 109In have been measured from 13 to 50 MeV with the help of the stack-foil technique. Since the silver target used has two odd mass stable isotopes of about equal abundance, 107Ag (51.83%) and 109Ag (48.17%), in some cases the residual nuclei are the same through different reaction channels but the Q-values are different. In these cases the experimental cross-sections are separated out by using the ratio of theoretical cross-sections of the same reaction. The experimental results were compared with calculated values obtained by means of the geometry-dependent hybrid (GDH) model. The initial exciton number n 0 = 4 with different configurations was tested. It was found that the configuration (2 n + 2 p + 0 h) appears to give a good fit to the experimental data.