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Application of modelling and simulation for optimization of a continuous fermentation process

Authors
Journal
Computers & Chemical Engineering
0098-1354
Publisher
Elsevier
Publication Date
Volume
17
Identifiers
DOI: 10.1016/0098-1354(93)80226-d
Keywords
  • Food Process
  • Continuous Fermentation Process
  • Process Optimization
  • Dynamic Simulation
  • Segregated Model
Disciplines
  • Biology
  • Economics

Abstract

Abstract Glutamic acid, a very important amino acid, is industrially produced by fermentation in batch processes. Continuous processes are often more economic. After identification of the biological system we can show that a two-stage cascade yields higher productivities than a standard batch or a one-stage continuous process. A segregated model dynamically simulates variing age distributions very well. Using results from simulation and fermentation runs in parallel saves a lot of time for the optimization of our process.

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