Abstract We examined the internal consistency, test–retest reliability, and the responsiveness of the Bruininks–Oseretsky Test of Motor Proficiency-Second Edition (BOT-2) for children with intellectual disabilities (ID). One hundred children with ID aged 4–12 years tested on 3 separate occasions: two baseline measurements with a 2-week interval before the intervention, and a follow-up measurement after 4 months of pediatric rehabilitation program. The test–retest reliability and internal consistency of the total scale were excellent, with an ICC of 0.99 (95% confidence interval) and α of 0.92. Responsiveness was acceptable for all BOT-2 measures except the balance subtest. The minimal detectable change (MDC) and the minimal important difference (MID) values yielded a lower sensitivity level but a higher specificity level. Implications for interpreting these responsiveness indices are discussed.