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Tumour-associated antigens in lung cancer: the possibility for a serologic assay.

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Publication Date
Source
PMC
Keywords
  • Research Article
Disciplines
  • Biology

Abstract

Methods were developed to obtain a purified tumour-associated antigen from squamous cell bronchogenic carcinoma of humans. From the preparation a highly specific antitumour antiserum was produced in rabbits. The antiserum was applied to an enzyme-linked immunosorbent assay that subsequently was used as a serologic test for lung cancer. Serum obtained preoperatively from patients with stage I lung cancer was found to be inhibitory in the assay system when compared with serum from healthy individuals.

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