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Osteogenesis imperfecta congenita: A connective tissue diathesis

Authors
Journal
The Journal of Pediatrics
0022-3476
Publisher
Elsevier
Publication Date
Volume
41
Issue
6
Identifiers
DOI: 10.1016/s0022-3476(52)80292-6

Abstract

Summary A case of osteogenesis imperfectain a newborn infant has been reported. The failure of reticulum to differentiate into mature collagen has been demonstrated in the corium, sclera, and cornea. The presence of a material in the bones which stains intensely with the periodic acid-Schiff technique and which may be an immature form of bone matrix has been described.

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